Josephine Watiri Michuki, the widow of former Environment minister John Michuki, has died.
Mrs Michuki died at the Nairobi Hospital Wednesday morning where she was undergoing treatment.
"Very, very painful. Our mother-in law, Mrs Josephine Michuki, died early today at Nairobi hospital," said former Information minister Mutahi Kagwe on his Facebook page.
"Good people, we desperately need your prayers."
Mr Kagwe is a son-in-law of the Michukis.
Prime Minister Raila Odinga said Mrs Michuki's death was "a double blow to the family of the late honourable Michuki".
"She was a strong and courageous woman who had shown she was capable of stepping into her late husband's shoes and provide guidance to our people on development and political issues," mourned Mr Odinga.
"I pray for the family and friends at this time of grief."
Deputy Prime Minister Uhuru Kenyatta also mourned the late Mrs Michuki.
"I'm saddened by the death of Josephine Michuki. I pray that God gives the Michuki family strength and comfort," he said.
Her death comes months after Mr Michuki passed on. The minister died in February, aged 80.