Sigoti Girls Secondary School in Nyakach, Kisumu County, has been closed down following fire incidents that razed two dormitories.
One of the dormitories caught fire on Friday and the other Saturday morning around 8am.
Principal Rose Ndiga said students in form one, two and three have been told to report back to school in a fortnight while those in form four are expected back after a week.
"The damage is extensive and we have decided to send the girls home as we assess the damage and repair the dormitory to make it conducive again for our students," Ms Ndiga said.
County Commissioner Mohamed Maalim confirmed that there were no casualties.
"We thank God because in the two fire incidences no student was hurt. We are continuing with investigations to establish the cause of the blaze," Mr Maalim said.
There was also a similar incident at Moi Girls School, Nairobi, on Saturday morning that has so far claimed at least seven lives.
Education Cabinet Secretary Fred Matiang’i said 10 other students were injured and are admitted to hospital.
"Out of the 10, two are in critical condition, doctors have told us the other eight are out of danger," he said.
President Uhuru Kenyatta and Mr Raila Odinga sent condolence messages to the family of the victims.